Antibacterial evaluation of the methanolic extract of the leaf and stem bark of Enantia chlorantha

Abstract

Studies on the antibacterial activity of methanolic extracts of the stem bark and leaf of Enantia chlorantha, were carried out. The antibacterial activity of the methanolic extract was studied using agar well diffusion and tube dilution methods. The bacteria used were Salmonella typhi, Pseudomonas aeruginosa, and E. coli. The results revealed that the methanolic extract of the stem bark of E. chlorantha showed wider zones of inhibition on the bacterial isolates than the leaf extract. The zone of inhibition decreases with the decrease in concentration in both methanolic extract of the leaf and stem bark. The Minimum Inhibitory Concentration (MIC) of the methanolic extract of both stem bark and leaf ranged from 12.5mg/ml to 25mg/ml, while Minimum Bactericidal Concentration (MBC) of the methanolic extract of both leaf and stem bark were at 50mg/ml respectively. The result suggests that the extract possess some active components that may be used for the development of therapeutic agents for the treatment of ailments associated with the test organisms.