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http://repository.futminna.edu.ng:8080/jspui/handle/123456789/5986| Title: | Synthesis, Spectroscopic And Inhibitory Study Of Some Substituted Schiff Bases |
| Authors: | Salihu, Simon Olonkwoh |
| Keywords: | Schiff base, antimicrobial activity, substituent, aniline |
| Issue Date: | Feb-2017 |
| Publisher: | International Journal of Innovative Research and Advanced Studies |
| Abstract: | A series of Schiff bases namely (E)-4-methoxy-2-((phenylimino)methyl)phenol [I], (E)-2-(((4-chlorophenyl)imino)methyl)-4-methoxyphenol [II], (E)-2-(((2-hydroxyphenyl)imino)methyl)-4-methoxyphenol [III], (E)-2-(((5-chloro-2-methylphenyl)imino)methyl)-4-methoxyphenol [IV] derived from substituted aniline and 5-methoxysalicylaldehyde were synthesized and characterized by elemental analysis, IR, UV, and 1H NMR. The results revealed that the compounds are capable to prevent the growth Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Streptococcus agalactiae, Staphylococcus aureus and Salmonella typhimurium in diverse concentrations. The growth prevention capability was affected by the substituent on the aniline. |
| Description: | The authors appreciate the Organization of Women in Science in Developing World for the research fellowship granted to Demehin, A.I. to study in the Department of Chemistry, University of Malaya, Kuala Lumpur, Malaysia. They are grateful to Prof. Dr. Hapipah, M. A. Department Of Chemistry, University of Malaya for providing for the NMR analyses and allowing the use of her laboratory for the research. They express their profound gratitude to Dr. Ololade, Z.S. of Department of Chemical Sciences, Bells University, Ota, Nigeria who helped with the antimicrobial analyses. Also, the authors acknowledge the management of Adeyemi College of Education, Ondo, Nigeria for granting Demehin, A.I. a study leave. |
| URI: | http://repository.futminna.edu.ng:8080/jspui/handle/123456789/5986 |
| ISSN: | 2394-4404 |
| Appears in Collections: | Chemistry |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| OLoyede-Akinsulere etal 2017-Synthesis, Spectroscopic And Inhibitory Study Of Some Substituted Schiff Bases .pdf | Article | 294.05 kB | Adobe PDF | View/Open |
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