Please use this identifier to cite or link to this item: http://repository.futminna.edu.ng:8080/jspui/handle/123456789/587
Title: The Effect of T. b. brucei Infections on Total Lipid Profile of Rat Erythrocyte Ghost Membrane.
Authors: Abubakar, A.
Akanji, M. A.
Issue Date: 1999
Publisher: Biotechnology Society of Nigeria
Abstract: White albino rats were infected with 106 T.b.brucei parasites (Federe/CT/28/NITR) per rat and levels of parasitaemia and Packed Cell Volume (PCV) were monitored daily. Erythrocytes were harvested and ghost membrane prepared daily for total phospholipid and neutral lipid analysis. The result showed a significant decrease in PCV values with an increase in parasitaemia (p<0.01). There was also a significant variations in total lipid components of erythrocyte ghost membrane of infected animals and values such as 76.9% and 104.2% of control values for total phospholipids and neutral lipids respectively were obtained (P<0.05). This implies an abnormal lipid composition of erythrocyte membrane which can cause it's damage resulting into anaemia.
URI: http://repository.futminna.edu.ng:8080/jspui/handle/123456789/587
ISSN: 0189-1731
Appears in Collections:Biochemistry

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