Effect of Different aqueous Extracts of Garlic on some Electrolyte and Urea Levels in Rats

Abstract

Studies on the effect of fresh and dry aqueous extracts of garlic (hot and cold) on Na+, K+, Cl-, HCO- and urea levels of rats were carried out. Animals were divided into 5 groups of 5 rats each. Groups I and II were treated with fresh cold and hot extract respectively while groups III and IV received dried cold and hot extract respectively. Group V served as untreated control. Treatment was oral administration at 100mg/kg bodyweight for seven consecutive days. Analysis of the results showed significant (P<0.05) decrease in Na+ and Cl- levels of the treated groups when compared with the control. However the reduction in the levels of K+ and HCO3- was insignificant(P>0.05). The extracts appear not to have effect on the urea level when compared with the control group. The decrease observed in these electrolytes were more with fresh cold extract than with others. The results therefore suggest that fresh cold garlic extract may useful in the management of elctrlyte related disorders.