Effect of Extracts of Fermented Wheat and Garlic bulbs on some haematological and electrolytes parameters in T. brucei-infected rats.

Abstract

Serum haematological and electrolyte concentrations were assessed in rats infected with federe strain of Trypanosoma brucei treated with wheat and garlic extracts. The results showed significant increase in haemoglobin (Hb) concentration, packed cell volume (PCV) and red blood cell (RBC) count of infected treated group when compared with infected untreated (control) group. While the white blood cell (WBC) count increase significantly in infected untreated group, results showed a significant increase (p<0.05) during infection in Na+ concentration of infected untreated group when compared with other experimental groups. While there were no significant (p<0.05) difference in the level of K+, Po4, and HCO3 in all experimental groups, there was significant increase (p< 0.05) in Cl- concentration in all experimental groups when compared with uninfected untreated (control). Results suggest that these plants have greater potential in the management of African trypanosomiasis.