ANTIBACTERIAL EVALUATION OF Buchholzia coriacea SEED EXTRACTS

Abstract

The antimicrobial resistance of microorganisms makes them untreatable using the convectional antibiotics, therefore a need for alternative routes of treatment. Among several different alternative Buchholzia coriacea (wonderful kola) is an effective choice because of its numerous phytochemical components. The wonderful kola sample used in this study was purchase from Kure market in Niger State, Nigeria. The phytochemical screening, antibacterial susceptability test, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were performed using standard methods. The phytochemical analysis revealed the presence of alkaloids, tanins, flavonoids, steriod and the absence of saponins. Antibacterial activity of wonderful kola on some medically important bacteria; Staphylococcus aureus, Streptococcus pneumonia and Klebsiella pneumonia shows wonderful kola seed exhibit antibacterial acitivity producing zone of inhibition against all tested bacteria and has the highest zone of inhibition at 250 mg/ml concentration. The results from this study show that wonderful kola seed could be used as an antibacterial agent and also be used for the development of therapeutic agents for the treatment of ailment associated with the test organisms.