Please use this identifier to cite or link to this item:
http://repository.futminna.edu.ng:8080/jspui/handle/123456789/11381
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jigam, A.A | - |
dc.contributor.author | Akanya, H.O | - |
dc.contributor.author | Dauda, B.E.N | - |
dc.contributor.author | Okogun, J.O | - |
dc.date.accessioned | 2021-07-24T13:24:50Z | - |
dc.date.available | 2021-07-24T13:24:50Z | - |
dc.date.issued | 2010-06-28 | - |
dc.identifier.citation | Ali, A.Jigam, Helmina, O. Akanya, Bukar, E.N. Dauda and Okogun, J.O. (2010) Polygalloytannin isolated from the roots of Acacia nilotica Del (Leguminoscease) is effective against Plasmodium berghei in mice. . Journal of Medicinal Plants Research 4 (12), pp1169- 1175 | en_US |
dc.identifier.issn | 1996-0875 | - |
dc.identifier.uri | http://repository.futminna.edu.ng:8080/jspui/handle/123456789/11381 | - |
dc.description | Full Length Research Paper | en_US |
dc.description.abstract | Crude methanolic root extracts of Acacia nilotica Del. (Leguminoseae)demonstrated significant activity against chloroquine sensitive strain ofPlasmodium berghei in mice. Purified extracts showed only a single fraction with significant antiplasmodial effects using bioguided essay techniques. The activeA. nilotica isolate was highly polar dissolving readily in methanol, appeared as a single spot in different TLC conditions and was positive for tannins, melting with decomposition between 224 - 229°C. Its 1H NMR spectra exhibited large signals at S 6.90 - 7.58 and 4.70 - 5.00. The Mass spectra (ES1 - Msn) of the isolate gave a large M - 1 signal of m/z 1395 consistent with the molecular formula C62H43O38. Others at 1243, 1091, 939, 787, 635, 453 and 331 that differ by m/z 152 were accounted for by the progressive loss of a galloyl (C7H4O4) moiety. A polygalloyltannin structure containing a central glucosyl moiety corresponding with 1, 3, 6 – digalloyl – 2, 4 monogalloyltannin was hence postulated. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Journal of Medicinal Plants Research | en_US |
dc.relation.ispartofseries | Vol. 4;12 | - |
dc.subject | Acacia nilotica | en_US |
dc.subject | Plasmodium berghei | en_US |
dc.subject | 1H NMR spectra | en_US |
dc.subject | polygalloyltannin | en_US |
dc.title | Polygalloyltannin isolated from the roots of Acacia nilotica Del. (Leguminoseae) is effective against Plasmodium berghei in mice | en_US |
dc.type | Article | en_US |
Appears in Collections: | Biochemistry |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Polygalloytannin isolated from the roots of Acacia nilotica Del (Leguminoscease) is effective against Plasmodium berghei in mice..pdf | 255.16 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.