F. A. OguntoluD. W. YavalahC. F. UdomT. A. AyoolaA. A. Victor2025-05-062022-06-25F. A. Oguntolu, D. W.Yavalah, C. F. Udom, T. A. Ayoola & A. A. Victor (2022). A Mathematical Modeling of Lymphatic Filariasis and Malaria Co-infection. ATBU Journal of Science, Technology and Education. 10(2). 95-110. ISSN:2277-0011 http://www.atbuftejoste.com/index.php/joste/article/view/4242277-0011http://repository.futminna.edu.ng:4000/handle/123456789/1923Lymphatic Filariasis (LF) and Malaria continue to pose significant public health burden globally and are co-endemic in many sub-Saharan African regions. In this work, we developed and analyzed a mathematical model of Lymphatic filariasis and malaria co-infection model. Friedman and Lunge method was used to find the positivity of the solution, the disease-free equilibrium was obtained, the model stability was analyzed, and the basic reproductive number was also obtained. The findings suggest that with the use of a bed-net and insecticide as a control measure, the treatment of LF and malaria co-infection can be reduced to a minimum.enLymphatic filariasismalariacoinfectiontreatmentbed-netinsecticidesArticle