F. A. OguntoluO. J. PeterB. I. OmedeT. A. AyoolaG. B. Balogun2025-05-052025-06F. A. Oguntolu, O. J. Peter, B. I. Omede, T. A. Ayoola & G. B. Balogun (2025). Exploring the dynamics of lymphatic filariasis through a mathematical model and analysis with Holling type II treatment functions. Iranian Journal of Numerical Analysis and Optimization, 15(Issue 2), 531-569. https://doi.org/10.22067/ijnao.2025.89033.1482http://repository.futminna.edu.ng:4000/handle/123456789/1867This paper presents a robust deterministic mathematical model incorporat-ing Holling type II treatment functions to comprehensively investigate the dynamics of Lymphatic filariasis. Through qualitative analysis, the model demonstrates the occurrence of backward bifurcation when the basic re-production number is less than one. Moreover, numerical simulations are employed to illustrate and validate key analytical findings. These simula-tion results emphasize the significance of accessible medical resources and the efficacy of prophylactic drugs in eradicating Lymphatic filariasis. The findings show that, enhancing medical resource availability and implement-ing effective treatment strategies in rural areas and regions vulnerable to Lymphatic filariasis is crucial for combating the transmission and control of this disease.enLymphatic filariasisHolling type II treatment functionRepro-duction numberStabilityBifurcationArticle