Direct and indirect transmission of typhoid fever model with optimal control
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Date
2021-08
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier BV
Abstract
In this paper, a model for direct and indirect transmission dynamics of typhoid fever with three control interventions is analyzed. Optimal control strategies are proposed to minimize both the disease burden and the intervention cost. We proved the existence and uniqueness of optimal control paths and obtained these optimal paths analytically using Pontryagin’s Maximum Principle. We analyzed our results numerically to compare various strategies of proposed controls. It is observed that the implementation of the three controls among all strategies is most successful. Thus, we conclude that in order to reduce typhoid fever threat, all the three controls must be taken into consideration concurrently.
Description
Keywords
Optimal control, Typhoid fever, Early treatment
Citation
O. J. Peter, M. O. Ibrahim, H. O. Edogbanya, F. A. Oguntolu, K. Oshinubi, A. A. Ibrahim, T. A. Ayoola & J. O. Lawal. (2021). Direct and indirect transmission of typhoid fever model with optimal control. Results in Physics, 27, 104463. https://doi.org/10.1016/j.rinp.2021.104463