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Item Mathematical model of COVID-19 transmission dynamics incorporating booster vaccine program and environmental contamination(2022-11-12) Akinwande, N. I.; Ashezua, T. T.; Gweryina, R. I.; Somma, Samuel Abu; Oguntolu, F. A.; Usman, A.COVID-19 is one of the greatest human global health challenges that causes economic meltdown of many nations. In this study, we develop an SIR-type model which captures both human-to-human and environment-to-human-to-environment transmissions that allows the recruitment of corona viruses in the environment in the midst of booster vaccine program. Theoretically, we prove some basic properties of the full model as well as investigate the existence of SARS-CoV-2-free and endemic equilibria. The SARS-CoV-2-free equilibrium for the special case, where the constant inflow of corona virus into the environment by any other means, Ωis suspended (Ω =0)is globally asymptotically stable when the effective reproduction number 𝑅0𝑐<1and unstable if otherwise. Whereas in the presence of free-living Corona viruses in the environment (Ω >0), the endemic equilibrium using the centremanifold theory is shown to be stable globally whenever 𝑅0𝑐>1. The model is extended into optimal control system and analyzed analytically using Pontryagin’s Maximum Principle. Results from the optimal control simulations show that strategy E for implementing the public health advocacy, booster vaccine program, treatment of isolated people and disinfecting or fumigating of surfaces and dead bodies before burial is the most effective control intervention for mitigating the spread of Corona virus. Importantly, based on the available data used, the study also revealed that if at least 70%of the constituents followed the aforementioned public health policies, then herd immunity could be achieved for COVID-19 pandemic in the community.Item Approximate Solution of SIR Infectious Disease Model Using Homotopy Pertubation Method (HPM).(Pacific Journal of Science and Technology, 2013-11-20) Abubakar, Samuel; Akinwande, N. I.; Jimoh, O. R.; Oguntolu, F. A.; Ogwumu, O. D.In this paper we proposed a SIR model for general infectious disease dynamics. The analytical solution is obtained using the Homotopy Perturbation Method (HPM). We used the MATLAB computer software package to obtain the graphical profiles of the three compartments while varying some salient parameters. The analysis revealed that the efforts at eradication or reduction of disease prevalence must always match or even supersede the infection rate.Item Stability Analysis of Disease Free Equilibrium (DFE) State of a Mathematical Model of Yellow Fever Incorporating Secondary Host(Pacific Journal of Science and Technology, 2017-11-20) Somma, Samuel Abu; Akinwande, N. I.; Jiya, M.; Abdulrahaman, S.In this paper we formulate a mathematical model of yellow fever incorporating secondary host. We obtained the Disease Free Equilibrium (DFE) Points and compute the basic reproduction number. The local and global stability of the DFE was analyzed using Jacobian Matrix stability techniques and Lyapunov function respectively. The local and global stability was asymptotically stable if 1 0 R and 1 0 R , respectively. The basic reproduction number and control parameters of the model were presented graphically.